Article
Identification of the crossing-over point of a hybrid gene encoding human glycophorin variant Sta. Similarity to the crossing-over point in haptoglobin-related genes.
The Journal of biological chemistry - 5 Jun 1990
Rearden A, Phan H, Dubnicoff T, Kudo S, Fukuda M
Abstract excerpt
One of the human glycophorin variants, Stones (Sta), has been shown to be the product of a hybrid gene of which the 5'-half derived from the glycophorin B (GPB) gene whereas the 3'-half derived from the glycophorin A (GPA) gene. The present study reveals the crossing-over point of this hybrid gen...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Crossing Over, Genetic
- Exons
- Genetic Variation
- Glycophorins
- Haptoglobins
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Sequence Homology, Nucleic Acid
- Sialoglycoproteins