Article
Defining molecular phenotypes of human papillomavirus-associated oropharyngeal squamous cell carcinoma: validation of three-class hypothesis.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Sept 2009
Weinberger Paul M, Yu Ziwei, Kountourakis Panteleimon, Sasaki Clarence, Haffty Bruce G, Kowalski Diane, Merkley Mark A, Rimm David L, Camp Robert L, Psyrri Amanda
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine if oropharyngeal squamous cell carcinoma (OSCC) classified into three groups based on human papillomavirus (HPV) 16 DNA presence and p16 expression display different protein expression patterns. STUDY DESIGN: Cross-sectional study. SETTING: A laboratory-based study of patients with OSCC treated at a tertiary care academic medical center. SUBJECTS AND METHODS:...
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