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Article

[Mutations in 21-hydroxylase gene caused by gene conversion-like events].

Fukuoka igaku zasshi = Hukuoka acta medica - 1 Feb 1990

Urabe K

Abstract excerpt

Two steroid 21-hydroxylase genes (CYP21A and CYP21B) alternate in tandem with two genes for the fourth component of complement (C4A and C4B) on the short arm of chromosome 6 between the loci of HLA-B and HLA-DR. The CYP21B gene encodes an adrenal microsomal cytochrome P-450, which is specific for steroid 21-hydroxylation (P450c21). A defect of this protein would cause 21-hydroxylase deficiency, which is an...

Topics

Gene Conversion
Genetics, Population
Humans
Japan
Mutation
Steroid 21-Hydroxylase
Steroid Hydroxylases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2328938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2328938-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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