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Article

Mutation and linkage disequilibrium analysis in genetic counselling of Spanish cystic fibrosis families.

Journal of medical genetics - 1 Nov 1991

Casals T, Nunes V, Lázaro C, Giménez F J, Girbau E, Volpini V, Estivill X

Abstract excerpt

We have analysed haplotypes for four DNA polymorphisms, closely linked to the cystic fibrosis (CF) gene, in 82 Spanish families, in which the CF probands are either homozygous for non-delta F508 mutations or heterozygous for the delta F508 deletion and other CF mutations. The analysis provides genetic data for a new polymorphism for the closely linked marker pKM.19, which is very strongly associated with CF....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1770534
DOI: 10.1136/jmg.28.11.771
PMCID: PMC1017113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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