Article
Human cytosolic adenylate kinase allelozymes; purification and characterization.
Biochimica et biophysica acta - 29 Mar 1990
Luz C M, König I, Schirmer R H, Frank R
Abstract excerpt
Cytosolic adenylate kinase (ATP + AMP in equilibrium 2 ADP:AMP phosphotransferase, EC 2.7.4.3) shows a balanced polymorphism of AK1*1 (95%) and AK1*2 (5%). AK1*2 occurs only in Caucasian populations and is common among hemophilia-A patients (László, A., Kósa, F., Zimányi, I. and Egyed, A. (1985) Acta Paediatr. Hung. 26, 87-96). 1. From 350 g heterozygous human muscle we purified 7.5 mg AK1*2 and 8.5 mg AK1*1. The...
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