Article
The classical human phosphoglucomutase (PGM1) isozyme polymorphism is generated by intragenic recombination.
Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 1993
March R E, Putt W, Hollyoake M, Ives J H, Lovegrove J U, Hopkinson D A, Edwards Y H, Whitehouse D B
Abstract excerpt
The molecular basis of the classical human phosphoglucomutase 1 (PGM1) isozyme polymorphism has been established. In 1964, when this genetic polymorphism was first described, two common allelozymes PGM1 and PGM1 2 were identified by starch gel electrophoresis. The PGM1 2 isozyme showed a greater...
Topics
- Alleles
- Base Sequence
- Blotting, Western
- DNA Primers
- Humans
- Isoenzymes
- Molecular Sequence Data
- Phosphoglucomutase
- Point Mutation
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length