Screening for epidermal growth factor receptor mutations in lung cancer.

doi:10.1056/NEJMoa0904554

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Article

Screening for epidermal growth factor receptor mutations in lung cancer.

The New England journal of medicine - 3 Sept 2009

Rosell Rafael, Moran Teresa, Queralt Cristina, Porta Rut, Cardenal Felipe, Camps Carlos, Majem Margarita, Lopez-Vivanco Guillermo, Isla Dolores, Provencio Mariano, Insa Amelia, Massuti Bartomeu, Gonzalez-Larriba Jose Luis, Paz-Ares Luis, Bover Isabel, Garcia-Campelo Rosario, Moreno Miguel Angel, Catot Silvia, Rolfo Christian, Reguart Noemi, Palmero Ramon, Sánchez José Miguel, Bastus Roman, Mayo Clara, Bertran-Alamillo Jordi, Molina Miguel Angel, Sanchez Jose Javier, Taron Miquel

Abstract excerpt

BACKGROUND: Activating mutations in the epidermal growth factor receptor gene (EGFR) confer hypersensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib in patients with advanced non-small-cell lung cancer. We evaluated the feasibility of large-scale screening for EGFR mutations in such patients and analyzed the association between the mutations and the outcome of erlotinib treatment. METHODS: From...

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PMID: 19692684
DOI: 10.1056/NEJMoa0904554

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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