Article
Strain specificity of bovine Theileria parva-specific cytotoxic T cells is determined by the phenotype of the restricting class I MHC.
Immunology - 1 Jan 1990
Goddeeris B M, Morrison W I, Toye P G, Bishop R
Abstract excerpt
To determine whether the major histocompatibility complex (MHC) phenotype of cattle could affect the parasite strain specificity of immunity to Theileria parva by influencing the antigenic specificity of Theileria-specific cytotoxic T lymphocytes (CTL), we investigated the parasite strain specificity of Theileria-specific CTL clones derived from cattle of different class I MHC phenotypes. Thirty-one class...
Topics
- Animals
- Antigens, Protozoan
- Apicomplexa
- Blotting, Western
- Cattle
- Cell Line
- Major Histocompatibility Complex
- Phenotype
- Polymorphism, Restriction Fragment Length
- T-Lymphocytes, Cytotoxic
- Theileriasis