Article
The cystic fibrosis gene is not likely to be involved in chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology - 1 Mar 1990
Gasparini P, Savoia A, Luisetti M, Peona V, Pignatti P F
Abstract excerpt
The etiology of chronic obstructive pulmonary disease (COPD) is still unknown, and both genetic and environmental factors may play a role. Some clinical aspects of COPD occur similarly in cystic fibrosis (CF), particularly in adult patients. A DNA polymorphic marker in strong linkage disequilibrium with the CF locus has been used to check the hypothesis that mutations of this locus might be involved in COPD. Its...
Topics
- Adult
- Aged
- Alleles
- Cystic Fibrosis
- DNA
- Female
- Genes
- Genetic Markers
- Humans
- Linkage Disequilibrium
- Lung Diseases, Obstructive
- Male