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Article

Mutation in the 3' region of the alpha-1-antitrypsin gene and chronic obstructive pulmonary disease.

Journal of medical genetics - 1 Oct 1997

Sandford A J, Spinelli J J, Weir T D, Paré P D

Abstract excerpt

A mutation in the 3' flanking region of the alpha-1-antitrypsin gene has been reported to be associated with chronic obstructive pulmonary disease (COPD). We have investigated the prevalence of this mutation in a group of 185 patients with airway obstruction and in 69 non-obstructed controls. The subjects were selected on the basis of their development of lung cancer and therefore had similar exposure to...

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Identifiers

PMID: 9350828
DOI: 10.1136/jmg.34.10.874
PMCID: PMC1051102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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