Article
Decreased expression of germinal center-associated nuclear protein is involved in chromosomal instability in malignant gliomas.
Cancer science - 1 Nov 2009
Ohta Kazutaka, Kuwahara Kazuhiko, Zhang Zhenhuan, Makino Keishi, Komohara Yoshihiro, Nakamura Hideo, Kuratsu Jun-ichi, Sakaguchi Nobuo
Abstract excerpt
Malignant glioma (MG) is highly proliferative and invasive, with the malignant characteristics associated with aneuploidy and chromosomal instability (CIN). Here, we found that the level of germinal center-associated nuclear protein (GANP), a mammalian homologue of yeast Sac3, was markedly decrea...
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