Article
A redox-active isopropylmalate dehydrogenase functions in the biosynthesis of glucosinolates and leucine in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Nov 2009
He Yan, Mawhinney Thomas P, Preuss Mary L, Schroeder Amy C, Chen Bing, Abraham Linda, Jez Joseph M, Chen Sixue
Abstract excerpt
We report a detailed functional characterization of an Arabidopsis isopropylmalate dehydrogenase (AtIPMDH1) that is involved in both glucosinolate biosynthesis and leucine biosynthesis. AtIPMDH1 shares high homology with enzymes from bacteria and yeast that are known to function in leucine biosynthesis. In plants, AtIPMDH1 is co-expressed with nearly all the genes known to be involved in aliphatic glucosinolate...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Chloroplasts
- Computational Biology
- DNA, Bacterial
- DNA, Plant
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Plant
- Genetic Complementation Test
- Glucosinolates
- Leucine
- Malate Dehydrogenase