Article
Single nucleotide polymorphisms, haplotypes and combined genotypes of lactoferrin gene and their associations with mastitis in Chinese Holstein cattle.
Molecular biology reports - 1 Jan 2010
Huang Jinming, Wang Hongmei, Wang Changfa, Li Jianbin, Li Qiuling, Hou Minghai, Zhong Jifeng
Abstract excerpt
Lactoferrin (Lf) is naturally produced by the mammary gland, having biological functions of antibacterial and anti-inflammatory activities. To investigate whether the Lf gene is associated with mastitis in dairy cattle, a DNA sequencing approach was used to identify single nucleotide polymorphisms (SNPs) in the gene. Three previously reported SNPs in the 5' flanking region and one novel SNP in exon1 of Lf gene...
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