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Article

Oncolytic adenoviruses targeted to cancer stem cells

1 Aug 2009

Abstract excerpt

Cancer stem cells (CSC) represent a distinct subpopulation of cancer cells of integral importance. CSCs embody the refractory nature observed among many cancers: very competent initial tumor establishment and extremely aggressive metastatic nature. Recent discoveries indicate that CSCs embody chemo- and radioresistance and have been correlated with advanced disease and resistance to current therapies, and thus...

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PMID: 19671759
DOI: 10.1158/1535-7163.mct-09-0367

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