Article
[Experimental analysis of microRNAs related to cardiac development differential expression].
Zhonghua yi xue za zhi - 26 May 2009
Shi Xiang-xiang, Lai Dan-dan, Zhang Jia-ying, Chu Mao-ping, Wang Sai-bin, Ni Qiu-ming, Huang Xiao-yan, Zhang Huai-qin, Yang De-ye
Abstract excerpt
OBJECTIVE: To investigate the differential expression profiles of microRNAs in the knockout Pax-8 mice by miRNA microarray analysis and study the function of microRNA during cardiac development. METHODS: The knockout Pax-8 mice model was established and the total RNA derived from Pax-8 KO-/- and Pax-8 KO+/- mice heart. MicroRNA microarray containing 567 mammalian microRNA probes was used to investigate the...
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