Article
Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans.
Proceedings of the National Academy of Sciences of the United States of America - 25 Aug 2009
Schroeckh Volker, Scherlach Kirstin, Nützmann Hans-Wilhelm, Shelest Ekaterina, Schmidt-Heck Wolfgang, Schuemann Julia, Martin Karin, Hertweck Christian, Brakhage Axel A
Abstract excerpt
Fungi produce numerous low molecular weight molecules endowed with a multitude of biological activities. However, mining the full-genome sequences of fungi indicates that their potential to produce secondary metabolites is greatly underestimated. Because most of the biosynthesis gene clusters are...
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