Article
Lamivudine and adefovir resistance in children and young adults with chronic hepatitis B.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2010
Akman Sezin Asik, Kose Sukran, Halicioglu Oya
Abstract excerpt
OBJECTIVE: Long-term lamivudine (LAM) and adefovir (ADV) treatment has been found to induce the emergence of drug-resistant hepatitis B virus (HBV) in a significant number of patients with chronic hepatitis B (CHB) infection. The aim of our study was to evaluate the LAM and ADV mutations detected in our patient group. MATERIALS AND METHODS: Twenty-four patients diagnosed with CHB were enrolled in this study. The...
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