Gastrointestinal stromal tumors I: pathology, pathobiology, primary therapy, and surgical issues.

Abstract excerpt

Gastrointestinal stromal tumor (GISTs) are the most common connective tissue malignancies of the gastrointestinal (GI) tract, with an incidence on the order of 10-13 per million people per year. Primary therapy is usually surgical, but the recurrence rate of large, so-called high-risk tumors, with a high mitotic rate, or those arising from small bowel and colon/rectum is particularly high. The natural history,...

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• Gastrointestinal Stromal Tumors
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• Oncogenes
• Proto-Oncogene Proteins c-kit
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