Article
Influence of the VEGF-A 936C>T germinal polymorphism on tumoral VEGF expression in head and neck cancer.
Pharmacogenomics - 1 Aug 2009
Formento Jean-Louis, Etienne-Grimaldi Marie-Christine, Francoual Mireille, Pagès Gilles, Onesto Cercina, Formento Patricia, Chamorey Emmanuel, Dassonville Olivier, Poissonnet Gilles, Milano Gérard
Abstract excerpt
AIMS: Elevated tumoral vascular endothelial growth factor A (VEGF-A) expression is linked to poor survival in head and neck cancer patients. The aim of the present study was to analyze the influence of VEGF-A gene polymorphisms on tumoral VEGF-A expression and to test their prognostic value in he...
Topics
- Adult
- Aged
- Aged, 80 and over
- DNA, Neoplasm
- Disease-Free Survival
- Enzyme-Linked Immunosorbent Assay
- Female
- Gene Frequency
- Genotype
- Head and Neck Neoplasms
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide