Article
Influence of the VEGF-A 936C>T germinal polymorphism on tumoral VEGF expression in head and neck cancer.
Pharmacogenomics - 1 Aug 2009
Formento Jean-Louis, Etienne-Grimaldi Marie-Christine, Francoual Mireille, Pagès Gilles, Onesto Cercina, Formento Patricia, Chamorey Emmanuel, Dassonville Olivier, Poissonnet Gilles, Milano Gérard
Abstract excerpt
AIMS: Elevated tumoral vascular endothelial growth factor A (VEGF-A) expression is linked to poor survival in head and neck cancer patients. The aim of the present study was to analyze the influence of VEGF-A gene polymorphisms on tumoral VEGF-A expression and to test their prognostic value in head and neck cancer patients. MATERIALS & METHODS: VEGF-A polymorphisms at position -2578C>A, -1498T>C, -1154G>A,...
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