Article
A protocol comparison for the analysis of heat shock protein A1B +A1538G SNP.
Cell stress & chaperones - 1 Mar 2010
Contreras-Sesvold Carmen L, Sambuughin Nyamkhishig, Blokhin Andrei, Deuster Patricia A
Abstract excerpt
Heat shock proteins act as molecular chaperones, assist in peptide maturation, and transport nascent peptides across membranes. One commonly studied single nucleotide polymorphism (SNP) for one of the proteins is HSPA1B (+A1538G). However, several studies of this polymorphism have failed to achieve Hardy-Weinberg equilibrium (HWE) for their sample. We compared various published procedures for analyzing the HSPA1B...
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