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Analysis of Human Cytomegalovirus-Encoded MicroRNA Activity during Infection

6 Aug 2009

Abstract excerpt

MicroRNAs (miRNAs) are expressed in a wide variety of organisms, ranging from plants to animals, and are key posttranscriptional regulators of gene expression. Virally encoded miRNAs are unique in that they could potentially target both viral and host genes. Indeed, we have previously demonstrated that a human cytomegalovirus (HCMV)-encoded miRNA, miR-UL112, downregulates the expression of a host immune gene,...

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PMID: 19656885
DOI: 10.1128/jvi.01292-09

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