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Article

BRCA2 alteration is important in clear cell carcinoma of the ovary.

Clinical genetics - 1 Aug 2009

Goodheart M J, Rose S L, Hattermann-Zogg M, Smith B J, De Young B R, Buller R E

Abstract excerpt

BRCA2 has been shown to play a significant role in hereditary ovarian carcinoma. Several cases of clear cell carcinoma (CCC) of the ovary containing BRCA2 mutations have been identified. We hypothesize that sequence variants of the BRCA2 gene are common in CCC of the ovary. Multiple methods were utilized to detect BRCA2 genetic alterations in a cohort of 13 ovarian CCC. These included an LOH analysis for copy...

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Share to Adenocarcinoma, Clear Cell
Share to BRCA2 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 19656163
DOI: 10.1111/j.1399-0004.2009.01207.x

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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