Article
An HPV 16, 18, and 45 genotyping test based on Hybrid Capture technology.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2009
Thai Ha, Rangwala Sameera, Gay Tanya, Keating Kimberly, McLeod Sarah, Nazarenko Irina, O'Neil Dominic, Pfister Dana, Loeffert Dirk
Abstract excerpt
BACKGROUND: It has been shown that women positive for HPV 16 and HPV 18 have an increased risk of high-grade cervical intraepithelial neoplasia (CIN) compared with women positive for other high-risk (HR) HPV types. In addition, HPV 18 and HPV 45 have been closely linked to aggressive and difficult to detect adenocarcinomas. OBJECTIVES: To develop a test based on the Hybrid Capture technology capable of...
Topics
- Cervix Uteri
- Cross Reactions
- DNA, Viral
- Female
- Genotype
- Human papillomavirus 16
- Human papillomavirus 18
- Humans
- Molecular Diagnostic Techniques
- Nucleic Acid Hybridization