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Article

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III β‐tubulin

31 Jul 2009

Abstract excerpt

Glioblastoma multiforme (GBM) is the most common and deadliest form of primary brain cancer in adults. Despite advances in molecular biology and genetics of gliomas currently there is no effective treatment or promising molecularly targeted experimental therapeutic strategies for these tumors. In previous studies we have shown aberrant overexpression of the class III beta-tubulin isotype (betaIII-tubulin) in GBM...

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PMID: 19650075
DOI: 10.1002/jcp.21870

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