Article
Incomplete penetrance and variable expressivity: is there a microRNA connection?
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Sept 2009
Ahluwalia Jasmine K, Hariharan Manoj, Bargaje Rhishikesh, Pillai Beena, Brahmachari Vani
Abstract excerpt
Incomplete penetrance and variable expressivity are non-Mendelian phenomena resulting in the lack of correlation between genotype and phenotype. Not withstanding the diversity in mechanisms, differential expression of homologous alleles within cells manifests as variations in penetrance and expressivity of mutations between individuals of the same genotype. These phenomena are seen most often in dominantly...
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