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Calorie Restriction Enhances T-Cell-Mediated Immune Response in Adult Overweight Men and Women

28 Jul 2009

Abstract excerpt

Calorie restriction (CR) enhances immune response and prolongs life span in animals. However, information on the applicability of these results to humans is limited. T-cell function declines with age. We examined effects of CR on T-cell function in humans. Forty-six overweight, nonobese participants aged 20-42 years were randomly assigned to 30% or 10% CR group for 6 months. Delayed-type hypersensitivity (DTH),...

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PMID: 19638417
DOI: 10.1093/gerona/glp101

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