Article
Caught at its own game: regulatory small RNA inactivated by an inducible transcript mimicking its target.
Genes & development - 1 Sept 2009
Figueroa-Bossi Nara, Valentini Martina, Malleret Laurette, Fiorini Francesca, Bossi Lionello
Abstract excerpt
A relevant, yet little recognized feature of antisense regulation is the possibility of switching roles between regulatory and regulated RNAs. Here we show that induction of a Salmonella gene relies on the conversion of a small RNA from effector to regulatory target. The chiP gene (formerly ybfM), identified and characterized in the present study, encodes a conserved enterobacterial chitoporin required for uptake...
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