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Article

Phospholamban gene mutations are not associated with hypertrophic cardiomyopathy in a Northern Greek population.

Biochemical genetics - 1 Dec 2005

Kalemi Theodora, Efthimiadis Georgios, Zioutas Dimitrios, Lambropoulos Alexandros, Mitakidou Anastasia, Giannakoulas Georgios, Vassilikos Vassilios, Karvounis Haralambos, Kotsis Alexandros, Parharidis Georgios, Louridas Georgios

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a genetically transmitted cardiac disease characterized by unexplained myocardial hypertrophy and diverse clinical spectrum. Currently, more than 250 HCM-related mutations in 10 genes encoding contractile sarcomeric proteins have been identified. Phospholamban (PLN) is a modest modulator of intracellular Ca2+ homeostasis and may be a candidate gene responsible for...

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Identifiers

PMID: 16382369
DOI: 10.1007/s10528-005-9121-8

Genes

PLN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Phospholamban gene mutations are not associated with hypertrophic cardiomyopathy in a Northern Greek population.PMID 16382369Read ↗

Phospholamban gene mutations are not associated with hypertrophic cardiomyopathy in patients from southern Poland.Semantic proximity Read ↗

PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing.Semantic proximity Read ↗

Prevalence and cardiac phenotype of patients with a phospholamban mutationSemantic proximity Read ↗

Genetic landscape of phospholamban cardiomyopathiesSemantic proximity Read ↗

Mutation of the phospholamban promoter associated with hypertrophic cardiomyopathy.Semantic proximity Read ↗

A study in Polish patients with cardiomyopathy emphasizes pathogenicity of phospholamban (PLN) mutations at amino acid position 9 and low penetrance of heterozygous null PLN mutations.Semantic proximity Read ↗

No evidence for an association between the -36A>C phospholamban gene polymorphism and a worse prognosis in heart failure.Semantic proximity Read ↗

Mutations in the human phospholamban gene in patients with heart failureSemantic proximity Read ↗

Phospholamban p.arg14del mutation in a Spanish family with arrhythmogenic cardiomyopathy: evidence for a European founder mutation.Semantic proximity Read ↗

Identification of the genotypes causing hypertrophic cardiomyopathy in northern Sweden.Semantic proximity Read ↗

A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.Semantic proximity Read ↗

Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.Semantic proximity Read ↗

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