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Article

Identification of compounds that correlate with ABCG2 transporter function in the National Cancer Institute Anticancer Drug Screen.

Molecular pharmacology - 1 Nov 2009

Deeken John F, Robey Robert W, Shukla Suneet, Steadman Kenneth, Chakraborty Arup R, Poonkuzhali Balasubramanian, Schuetz Erin G, Holbeck Susan, Ambudkar Suresh V, Bates Susan E

Abstract excerpt

ABCG2 is an ATP-binding cassette transporter that counts multiple anticancer compounds among its substrates and is believed to regulate oral bioavailability as well as serve a protective role in the blood-brain barrier, the maternal-fetal barrier, and hematopoietic stem cells. We sought to determine whether novel compounds that interact with the transporter could be identified through analysis of cytotoxicity...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19633067
DOI: 10.1124/mol.109.056192
PMCID: PMC2774997

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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