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Article

Direct endonuclease digestion and multi-analysis of restriction fragment length polymorphisms by microchip electrophoresis.

Journal of pharmaceutical and biomedical analysis - 5 Dec 2009

Akamine Rie, Yatsushiro Shouki, Yamamura Shouhei, Kido Jun-ichi, Shinohara Yasuo, Baba Yoshinobu, Kataoka Masatoshi

Abstract excerpt

A high-performance multi-analysis system for genotypic mutation by means of restriction fragment length polymorphisms (RFLP) involving endonuclease treatment of PCR-amplified DNA on a microchip and subsequent analysis by microchip electrophoresis for DNA sizing was developed. A Hitachi SV1210 system, with which 12 samples can be analyzed on a plastic chip with good accuracy as to DNA sizing between 25 and 300 bp,...

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Source

Identifiers

PMID: 19616912
DOI: 10.1016/j.jpba.2009.06.034

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ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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