Article
Therapeutic options for triple-negative breast cancers with defective homologous recombination.
Biochimica et biophysica acta - 1 Dec 2009
Jaspers Janneke E, Rottenberg Sven, Jonkers Jos
Abstract excerpt
Breast cancer is the most common malignancy among women in developed countries, affecting more than a million women per year worldwide. Over the last decades, our increasing understanding of breast cancer biology has led to the development of endocrine agents against hormone receptor-positive tumors and targeted therapeutics against HER2-expressing tumors. However, no targeted therapy is available for patients...
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