Article
Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data.
European journal of cancer (Oxford, England : 1990) - 1 Dec 2009
Randerson-Moor Juliette A, Taylor John C, Elliott Faye, Chang Yu-Mei, Beswick Samantha, Kukalizch Kairen, Affleck Paul, Leake Susan, Haynes Sue, Karpavicius Birute, Marsden Jerry, Gerry Edwina, Bale Linda, Bertram Chandra, Field Helen, Barth Julian H, Silva Isabel Dos Santos, Swerdlow Anthony, Kanetsky Peter A, Barrett Jennifer H, Bishop D Timothy, Bishop Julia A Newton
Abstract excerpt
We have carried out melanoma case-control comparisons for six vitamin D receptor (VDR) gene single nucleotide polymorphisms (SNPs) and serum 25-hydroxyvitamin D(3) levels in order to investigate the role of vitamin D in melanoma susceptibility. There was no significant evidence of an association between any VDR SNP and risk in 1028 population-ascertained cases and 402 controls from Leeds, UK. In a second Leeds...
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