Article
Expression profiling of human genetic and protein interaction networks in type 1 diabetes.
PloS one - 17 Jul 2009
Bergholdt Regine, Brorsson Caroline, Lage Kasper, Nielsen Jens Høiriis, Brunak Søren, Pociot Flemming
Abstract excerpt
Proteins contributing to a complex disease are often members of the same functional pathways. Elucidation of such pathways may provide increased knowledge about functional mechanisms underlying disease. By combining genetic interactions in Type 1 Diabetes (T1D) with protein interaction data we have previously identified sets of genes, likely to represent distinct cellular pathways involved in T1D risk. Here we...
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