Article
Detection of fluoroquinolone resistance level in clinical canine and feline Escherichia coli pathogens using rapid real-time PCR assay.
Veterinary microbiology - 18 Nov 2009
Shaheen Bashar W, Wang Chengming, Johnson Calvin M, Kaltenboeck Bernhard, Boothe Dawn M
Abstract excerpt
Fluoroquinolones are used to treat infections caused by Escherichia coli in canine and feline veterinary patients, particularly those infecting the urinary tract. The gyrA gene is a primary target causing fluoroquinolone resistance in gram negative coliforms, with mutations in codons 83 and 87 generally associated with high-level of resistance E. coli clinical isolates. We have developed a fluorescence resonance...
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