Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ipriflavone pharmacokinetics in mutant Nagase analbuminemic rats.

Biopharmaceutics & drug disposition - 1 Sept 2009

Chung Hye J, Kang Hee E, Yang Kyung H, Kim Sung Y, Lee Myung G

Abstract excerpt

Ipriflavone, a derivative of naturally occurring isoflavones, was primarily metabolized in rats via hepatic CYP1A1/2 and 2C11. Protein and mRNA expression of CYP1A2 in the liver, reported to be increased in mutant Nagase analbuminemic rats (NARs), should influence the pharmacokinetic parameters o...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylglucosaminidase
Share to Aryl Hydrocarbon Hydroxylases
Share to Cytochrome P-450 CYP1A1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P450 Family 2

Share to Isoflavones

Share to Microsomes, Liver

Share to Rats, Mutant Strains

Share to Steroid 16-alpha-Hydroxylase

Source

Identifiers

PMID: 19591122
DOI: 10.1002/bdd.667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19591122-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Ipriflavone pharmacokinetics in mutant Nagase analbuminemic rats.PMID 19591122Read ↗

Pharmacokinetics of oltipraz in mutant Nagase analbuminemic rats.Semantic proximity Read ↗

Faster clearance of omeprazole in mutant Nagase analbuminemic rats: possible roles of increased protein expression of hepatic CYP1A2 and lower plasma protein binding.Semantic proximity Read ↗

Pharmacokinetics, tissue distribution and identification of putative metabolites of JI-101 - a novel triple kinase inhibitor in rats.Semantic proximity Read ↗

Pharmacokinetics of Rasagiline in Healthy Adult Chinese Volunteers with Various Genotypes: A Single-Center, Open-Label, Multiple-Dose Study.Semantic proximity Read ↗

Pharmacokinetics and pharmacodynamics of intravenous trasemide in mutant Nagase analbuminemic rats.Semantic proximity Read ↗

Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10.Semantic proximity Read ↗

Pharmacokinetics and pharmacodynamics of intravenous bumetanide in mutant Nagase analbuminemic rats: importance of globulin binding for the pharmacodynamic effects.Semantic proximity Read ↗

P-glycoprotein, but not multidrug resistance protein 4, plays a role in the systemic clearance of irinotecan and SN-38 in mice.Semantic proximity Read ↗

Transporter and metabolic enzyme-mediated intra-enteric circulation of SN-38, an active metabolite of irinotecan: A new conceptSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.