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Article

Ipriflavone pharmacokinetics in mutant Nagase analbuminemic rats.

Biopharmaceutics & drug disposition - 1 Sept 2009

Chung Hye J, Kang Hee E, Yang Kyung H, Kim Sung Y, Lee Myung G

Abstract excerpt

Ipriflavone, a derivative of naturally occurring isoflavones, was primarily metabolized in rats via hepatic CYP1A1/2 and 2C11. Protein and mRNA expression of CYP1A2 in the liver, reported to be increased in mutant Nagase analbuminemic rats (NARs), should influence the pharmacokinetic parameters of ipriflavone. In this study, the contribution of hepatic CYP2C11 and intestinal CYP1A protein to the metabolism and...

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Identifiers

PMID: 19591122
DOI: 10.1002/bdd.667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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