Article
Repeat-induced point mutation (RIP) as an alternative mechanism of evolution toward virulence in Leptosphaeria maculans.
Molecular plant-microbe interactions : MPMI - 1 Aug 2009
Fudal Isabelle, Ross Simon, Brun Hortense, Besnard Anne-Laure, Ermel Magali, Kuhn Marie-Line, Balesdent Marie-Hélène, Rouxel Thierry
Abstract excerpt
Three avirulence genes, AvrLm1, AvrLm6, and AvrLm4-7, were recently identified in Leptosphaeria maculans and found to be localized as solo genes within large noncoding, heterochromatin-like regions mainly composed of retrotransposons, truncated and degenerated by repeat-induced point mutation (RIP). The Rlm6 resistance gene has been overcome within 3 years in outdoor experiments in France and, here, we...
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