Article
Cadherin-11 controls otolith assembly: evidence for extracellular cadherin activity.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2009
Clendenon Sherry G, Shah Bijal, Miller Caroline A, Schmeisser Glen, Walter Amanda, Gattone Vincent H, Barald Kate F, Liu Qin, Marrs James A
Abstract excerpt
Cadherin-11/Cdh11 is expressed through early development and strongly during inner ear development (otic placode and vesicle). Here we show that antisense knockdown of Cdh11 during early zebrafish development interferes with otolith formation. Immunofluorescence labeling showed that Cdh11 expression was concentrated on and within the otolith. Cdh11 was faintly detected at the lateral surface (sites of cell-cell...
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