Article
Co-administration of monosialoganglioside and skeletal muscle cells on dorsal root ganglion neuronal phenotypes in vitro.
Cellular and molecular neurobiology - 1 Jan 2010
Wang Lihong, Li Hao, Liu Zhen, Xu Xiaobo, Wang Huaijing, Li Zhenzhong
Abstract excerpt
The neuropeptide-immunoreactive (IR) and neurofilament-IR neurons are two major phenotypical classes in dorsal root ganglion (DRG). Targets of neuronal innervation play a vital role in regulating the survival and differentiation of innervating neurotrophin-responsive neurons. Monosialoganglioside (GM1) has been considered to have a neurotrophic factor-like activity. Both GM1 and target skeletal muscle (SKM) cells...
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