Article
The pattern of pegylated interferon-alpha2b and ribavirin treatment failure in cirrhotic patients depends on hepatitis C virus genotype.
Antiviral therapy - 1 Jan 2009
Aghemo Alessio, Rumi Maria Grazia, Monico Sara, Prati Gian Maria, D'Ambrosio Roberta, Donato Maria Francesca, Colombo Massimo
Abstract excerpt
BACKGROUND: Failure of anti-hepatitis C therapy encompasses both primary non-response and post-treatment relapse. Treatment failure to pegylated interferon (PEG-IFN)-alpha2b and ribavirin (RBV) largely depends upon virus genotype, but the interaction between genotype, cirrhosis and pattern of treatment failure is unclear. We aimed to assess whether cirrhosis modifies the pattern of PEG-IFN-alpha2b and RBV...
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