Article
Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.
BMJ open diabetes research & care - 1 Apr 2023
Zulueta Mirella, Gallardo-Rincón Héctor, Martinez-Juarez Luis Alberto, Lomelin-Gascon Julieta, Ortega-Montiel Janinne, Montoya Alejandra, Mendizabal Leire, Arregi Maddi, Martinez-Martinez María de Los Angeles, Camarillo Romero Eneida Del Socorro, Mendieta Zerón Hugo, Garduño García José de Jesús, Simón Laureano, Tapia-Conyer Roberto
Abstract excerpt
INTRODUCTION: Gestational diabetes mellitus (GDM) is underdiagnosed in Mexico. Early GDM risk stratification through prediction modeling is expected to improve preventative care. We developed a GDM risk assessment model that integrates both genetic and clinical variables. RESEARCH DESIGN AND METHODS: Data from pregnant Mexican women enrolled in the 'Cuido mi Embarazo' (CME) cohort were used for development (107...
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