Article
Isolation of cobalt hyper-resistant mutants of Saccharomyces cerevisiae by in vivo evolutionary engineering approach.
Journal of biotechnology - 20 Aug 2009
Cakar Z Petek, Alkim Ceren, Turanli Burcu, Tokman Nilgün, Akman Süleyman, Sarikaya Mehmet, Tamerler Candan, Benbadis Laurent, François Jean M
Abstract excerpt
Cobalt is an important element with magnetic properties used in various industrial applications, but is also needed for biological activity. Very little is known about the cellular response of living systems to cobalt stress. Towards investigating this mechanism, we isolated individual Saccharomyces cerevisiae cells resistant to high cobalt concentrations up to 8 mmoll(-1), by employing four different 'in vivo'...
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