Article
Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD).
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Jul 2009
Magracheva Eugenia, Kozlov Serguei, Stewart Colin L, Wlodawer Alexander, Zdanov Alexander
Abstract excerpt
Proteins of the A-type lamin family, which consists of two members, lamin A and lamin C, are the major components of a thin proteinaceous filamentous meshwork, the lamina, that underlies the inner nuclear membrane. A-type lamins have recently become the focus of extensive functional studies as a...
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