Article
Association study of catechol-O-methyltransferase Val158Met polymorphism with personality traits in Japanese healthy volunteers.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Oct 2007
Ishii Genki, Suzuki Akihito, Oshino Shingo, Shiraishi Hiroaki, Matsumoto Yoshihiko, Otani Koichi, Goto Kaoru
Abstract excerpt
Catechol-O-methyltransferase (COMT) is one of the major enzymes for the degradation of catecholamines. It has been suggested that catecholaminergic neurotransmission is involved in characterization of personality. Previous studies on the association between the COMT Val158Met polymorphism and personality traits in healthy subjects have produced inconsistent results. Therefore, the relationship between this...
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