Article
Apolipoprotein E genotype modifies the risk of behavior problems after infant cardiac surgery.
Pediatrics - 1 Jul 2009
Gaynor J William, Nord Alex S, Wernovsky Gil, Bernbaum Judy, Solot Cynthia B, Burnham Nancy, Zackai Elaine, Heagerty Patrick J, Clancy Robert R, Nicolson Susan C, Jarvik Gail P, Gerdes Marsha
Abstract excerpt
OBJECTIVE: The goal was to evaluate polymorphisms of the APOE gene as modifiers of neurobehavioral outcomes for preschool-aged children with congenital heart defects, after cardiac surgery. METHODS: A prospective observational study with neurodevelopmental evaluation between the fourth and fifth birthdays was performed. Attention and behavioral skills were assessed through parental report. RESULTS: Parents of 380...
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