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Article

Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia

29 Jun 2009

Abstract excerpt

INTRODUCTION: Rheumatoid arthritis (RA) is a heterogeneous disease and its underlying molecular mechanisms are still poorly understood. Because previous microarray studies have only focused on long-standing (LS) RA compared to osteoarthritis, we aimed to compare the molecular profiles of early and LS RA versus control synovia. METHODS: Synovial biopsies were obtained by arthroscopy from 15 patients (4 early...

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PMID: 19563633
DOI: 10.1186/ar2744

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