Article
Prevalence of antiretroviral drug resistance among treatment-naive and treated HIV-infected patients in Venezuela.
Memorias do Instituto Oswaldo Cruz - 1 May 2009
Rangel Héctor Rafael, Garzaro Domingo José, Torres Jaime Rafael, Castro Julio, Suarez Jose Antonio, Naranjo Laura, Ossenkopp John, Martinez Nahír, Gutierrez Cristina, Pujol Flor Helene
Abstract excerpt
An in-house, low-cost method was developed to determine the genotypic resistance of immunodeficiency virus type 1 (HIV-1) isolates. All 179 Venezuelan isolates analysed belonged to subtype B. Primary drug resistance mutations were found in 11% of 63 treatment-naïve patients. The prevalence of resistance in isolates from 116 HIV-positive patients under antiretroviral treatment was 47% to protease inhibitors, 65%...
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