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Article

Search for pathogenetic variants of the SPRY2 gene in intestinal innervation defects.

Internal medicine journal - 1 May 2009

Borghini S, Duca M Di, Pini Prato A, Lerone M, Martucciello G, Jasonni V, Ravazzolo R, Ceccherini I

Abstract excerpt

SPRY2 is an inducible inhibitor of signalling mediated by tyrosine kinases receptors, whose targeting causes intestinal hyperganglionosis in mice. In this light, we have undertaken a mutational analysis of the SPRY2 gene in patients affected with intestinal neuronal dysplasia (IND), without detecting nucleotide changes in any of the 26 DNA samples analysed, with the exception of two already known polymorphic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19545245
DOI: 10.1111/j.1445-5994.2009.01907.x

Genes

SPRY2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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