Article
Reconstruction of an in vitro tissue-specific microenvironment to rejuvenate synovium-derived stem cells for cartilage tissue engineering.
Tissue engineering. Part A - 1 Dec 2009
He Fan, Chen Xiaodong, Pei Ming
Abstract excerpt
Joint injury results in cartilage lesions that are characterized by a poor repair response. Adult stem cells are immensely appealing for biological joint repair, such as cartilage tissue engineering and regeneration. However, adult stem cells gradually lose their stemness once they are removed from their in vivo niche for plating in plastic flasks. We utilized a tissue-specific stem cell, synovium-derived stem...
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