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Article

A novel, spontaneously immortalized, human prostate cancer cell line, Bob, offers a unique model for pre-clinical prostate cancer studies.

The Prostate - 1 Oct 2009

Attard Gerhardt, Rizzo Sian, Ledaki Ioanna, Clark Jeremy, Reid Alison H M, Thompson Alan, Khoo Vincent, de Bono Johann S, Cooper Colin S, Hudson David L

Abstract excerpt

INTRODUCTION: New in vitro models of castration-resistant prostate cancer (CRPC) are urgently required. METHODS: Trans-rectal needle biopsies (TRBP) of the prostate were performed for research purposes on progressing CRPC patients who had not received prior treatment to the prostate. Biopsies were immediately digested with collagenase and plated onto collagen-coated flasks with a feeder layer of 3T6 cells and...

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Identifiers

PMID: 19544327
DOI: 10.1002/pros.20997

Genes

ERG
ETV1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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