Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleotide sequence and association analysis of pig apolipoprotein-B and LDL-receptor genes.

Animal biotechnology - 1 Jan 2009

Pena R N, Cánovas A, Varona L, Díaz I, Gallardo D, Ramírez O, Noguera J L, Quintanilla R

Abstract excerpt

Three genes are the major determinants of heritable hypercholesterolemia diseases in humans: APOB, LDLR and LDLRAP1, which encode for proteins that physically interact to promote cholesterol uptake in the cell. We have carried out association analyses of these variants with serum cholesterol and triglycerides concentrations in a half-sib Duroc pig population. Given the structure of the population (six paternal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Apolipoproteins B

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cholesterol

Share to DNA, Complementary

Share to Receptors, LDL

Share to Species Specificity

Share to Sus scrofa

Share to Triglycerides

Source

Identifiers

PMID: 19544207
DOI: 10.1080/10495390902892518

Genes

APOB
LDLR
LDLRAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleotide sequence and association analysis of pig apolipoprotein-B and LDL-receptor genes.PMID 19544207Read ↗

Identification of a novel Arg-->Cys mutation in the LDL receptor that contributes to spontaneous hypercholesterolemia in pigs.Semantic proximity Read ↗

Evaluation of the causality of the low-density lipoprotein receptor gene (LDLR) for serum lipids in pigs.Semantic proximity Read ↗

Identification and association analysis of several hundred single nucleotide polymorphisms within candidate genes for back fat thickness in Italian Large White pigs using a selective genotyping approach.Semantic proximity Read ↗

A functional variant in the porcine APOA2 promoter alters hepatic gene expression via RORα.Semantic proximity Read ↗

Genetic variants in ABCA1 promoter affect transcription activity and plasma HDL level in pigs.Semantic proximity Read ↗

SNPs in the porcine PPARGC1a gene: interbreed differences and their phenotypic effects.Semantic proximity Read ↗

Association analysis with lipid traits of 2 candidate genes (LRP12 and TRIB1) mapping to a SSC4 QTL for serum triglyceride concentration in pigs.Semantic proximity Read ↗

Analysis of the porcine APOA2 gene expression in liver, polymorphism identification and association with fatty acid composition traits.Semantic proximity Read ↗

Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model.Semantic proximity Read ↗

Polymorphisms of the porcine androgen receptor gene affecting its amino acid sequence and expression level.Semantic proximity Read ↗

Association analyses between type 2 diabetes genes and obesity traits in pigs.Semantic proximity Read ↗

Nucleotide variability and haplotype heterogeneity at the porcine fat mass and obesity-associated (FTO) gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.